Nizoral cream is is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth. Nizoral cream is used to treat Athlete's foot (tinea pedis; ringworm of the foot); Ringworm of the body (tinea corporis); Ringworm of the groin (tinea cruris; jock itch); Seborrheic dermatitis; "Sun fungus" (tinea versicolor; pityriasis versicolor); and Yeast infection of the skin (cutaneous candidiasis).